Purpose
This study aimed to identify sex-specific predictors of microalbuminuria in patients with type 2 diabetes mellitus. Recognizing sex-based differences in risk factors may facilitate the early detection and prevention of diabetic kidney disease. Methods: A cross-sectional analysis was performed using data from the Korea National Health and Nutrition Examination Survey. Microalbuminuria was defined as a urinary albumin-to-creatinine ratio ≥30 mg/g. Multivariable complex sample logistic regression analyses were conducted separately for male and female. Independent variables included age, duration of diabetes, glycated hemoglobin (HbA1c), fasting blood sugar (FBS), triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C), TG, HDL-C, waist circumference, and systolic blood pressure (SBP). Results: The prevalence of microalbuminuria was higher in male than in female. In both sexes, longer diabetes duration and elevated SBP were associated with microalbuminuria. Among male, FBS, TG/HDL-C ratio, TG, and low HDL-C were significant predictors. In female, HbA1c showed the strongest association, followed by age and diabetes duration. Conclusion: Sex-specific differences were identified in the predictors of microalbuminuria among patients with type 2 diabetes. Incorporating these differences into early screening and individualized care strategies may help improve the prevention of diabetic kidney complications.

PURPOSE
Depression is a common sign of suffering among the patients with Parkinson's disease (PD). Frequent and severe neuropsychiatric symptoms lead to high levels of distress in patients and their caregivers, which results in the high levels of caregiver burden. The aim of this study was to determine the predictors of caregiver burden in caregivers of the patients with Parkinson's disease (PD).
METHODS
The study included 183 consecutive PD patients and their caregivers. Patients were assessed using the Hoehn and Yahr scale, Mini Mental State Examination (MMSE), Beck Depression Inventory (BDI), and Schwab and England Activities of Daily Living Scale. Caregivers' depressive symptoms were evaluated using the Caregiver Burden Inventor (CBI), BDI, and World Health Organization Quality of Life Scale.
RESULTS
All of the patients reported one or more neuropsychiatric symptoms. Patients' and caregivers' depressive symptoms, caregivers' age and education, time for caregiving, and quality of life were significantly associated with the increased caregiver burden. After controlling the level of education as a potential confounding variable, depression in both patients and caregivers, time for caregiving, and quality of life explained 45.6% of the variance in caregiver burden.
CONCLUSION
Substantial attention needs to be given to the early identification of depression in PD patients and their caregivers to improve caregivers' quality of life and burden.

Citations

• Factors influencing caregiver burden in families of hospitalised patients with lung cancer
  Ye Ji Seo, Heeok Park
  Journal of Clinical Nursing.2019; 28(9-10): 1979.     CrossRef

PURPOSE
Parkinson's disease (PD) has a high incidence of psychiatric comorbidity, specifically depression and anxiety. This study examined the effectiveness of group cognitive behavioral therapy (CBT) in treating depression and anxiety.
METHODS
The study included 42 participants, aged between 52 and 77 years, who were diagnosed with idiopathic Parkinson's disease (IPD) and reported suffering from depression and anxiety. Patients were attending a department of outpatient neurology at D University Schools of Medicine in B Metropolitan city. A structured telephone-administered cognitive behavioral therapy was conducted for eight weeks. A repeated measure ANOVA was used to analyze results at pretest, post-test, and four weeks follow up.
RESULTS
According to service method, there were significant differences between the two groups in depression, anxiety and stigma was significant difference between time (p<.05). Analysis of the interaction between time and service method revealed significant differences in depression and anxiety (p<.05).
CONCLUSION
The results suggest that telephoneadministered cognitive behavioral therapy may be effective and may provide opportunity to adapt to individual needs for treating depression and anxiety in patients with Parkinson's disease.

Citations

• Efficacy of cognitive behavioral therapy for anxiety and depression in Parkinson’s disease patients: an updated systematic review and meta-analysis
  Asmaa Zakria Alnajjar, Moaz Elsayed Abouelmagd, Abdulrahman Krayim, Maickel AbdelMeseh, Nagham Bushara, Yehia Nabil
  Neurological Sciences.2024; 45(11): 5277.     CrossRef
• Effects of Task-Based LSVT-BIG Intervention on Hand Function, Activity of Daily Living, Psychological Function, and Quality of Life in Parkinson’s Disease: A Randomized Control Trial
  YoungSeok Choi, DeokJu Kim, Kuan Lin Chen
  Occupational Therapy International.2022; 2022: 1.     CrossRef
• Concept Analysis of Self-stigma in Patients with Tuberculosis
  Seonmi Yeom, Jeong Hee Kang, Youngran Yang
  Journal of Korean Academy of Community Health Nursing.2021; 32(3): 312.     CrossRef
• Non-pharmacological treatment for Parkinson disease patients with depression: a meta-analysis of repetitive transcranial magnetic stimulation and cognitive-behavioral treatment
  Jianing Chen, Peikun He, Yuhu Zhang, Yuyuan Gao, Yihui Qiu, You Li, Qingxi Zhang, Limin Wang, Zhiheng Huang, Jiehao Zhao, Kun Nie, Lijuan Wang
  International Journal of Neuroscience.2021; 131(4): 411.     CrossRef
• Personalized Telemedicine for Depression in Parkinson’s Disease: A Pilot Trial
  Roseanne D. Dobkin, Alejandro Interian, John Logan Durland, Michael A. Gara, Matthew A. Menza
  Journal of Geriatric Psychiatry and Neurology.2018; 31(4): 171.     CrossRef
• Factors that affect Chronic Illness Anticipated Stigma(CIAS) in patients with Parkinson's disease
  Mi-Jung Kim, Eun-Sook Bae
  Korean Journal of Health Education and Promotion.2015; 32(3): 121.     CrossRef