PURPOSE
This study was to investigate the factors influencing the quality of life of patients with hemophilia and to provide the data for health promoting intervention in order to improve their quality of life.
METHOD
The subjects of this study were involved 186 male patients with hemophilia by convenience sampling. These results were analyzed statistically by frequency, percentage, t-test, ANOVA, Pearson Correlation Coefficient, and Stepwise multiple regression.
RESULTS
There were significant differences in the quality of life according to the frequency of bleeding. Quality of life showed negative relationships and health problems, bleeding, limitation of joint motion, and depression with stepwise Multiple Regression analysis for quality of life revealed that the most powerful predictor was depression. Depression, health problem, and limitation of joint motion accounted for 64.6% of the variance in the quality of life of patients with hemophilia.
CONCLUSION
Therefore it is necessary to develop nursing interventions with these variables to increase the quality of life for patients with hemophilia.

PURPOSE
This research was done to establish a theoretical foundation for the adjustment process of patients with hemophilia.
METHOD
For this study, 14 patients with hemophilia participated. The data was collected through the in-depth interviews and analysed in terms of Strauss and Corbin's grounded theory methodology.
RESULT
The core category was identified with "uncertainty". The adjustment process was classified into two stages: the 'unstable stage' before the moment they learn about the Hemophilia Foundation and the 'stable stage' since then. The two stages were further divided into four groups, namely 'the stage of isolation ', 'the stage of maintaining survival', 'the stage of pursuing hope', 'the stage of ambivalence'. The categories of these stages include a series of subcategories to describe the adjustment of patients. The quality of life for these patients has increasingly improved based on support from hemophiliac organizations. But due to the uncertainty of disease, the patients have four stages of adjustment process from the stage of isolation to that of ambivalence and might turn to feedback.
CONCLUSION
Therefore the nursing interventions reflecting adjustment process of patients with hemophilia should be developed.